WebJun 16, 2024 · The replication study analyzing 123 metabolic traits suggested that bisallylic groups levels and omega-3 fatty acids were inversely correlated with pancreatitis risk. … Webbi· al· le· lic (ˈ)bī-ə-ˈlē-lik, -ˈle-. : of, relating to, or affecting both alleles of a gene. The risk of colorectal cancer among carriers of biallelic mutations appears to be close to 100% by …
Docosahexaenoic and arachidonic acid peroxidation: It
Pancreatitis is a common disease featured by autodigestion of the pancreas (1). Acute pancreatitis can transit into recurrent episodes, and further progress into chronic pancreatitis (1). Several modifiable risk factors, including smoking, alcohol consumption, abdominal adiposity and obesity, gallstone diseases … See more Our comprehensive MR study reveals that elevated triglycerides levels and reduced degree of unsaturation in fatty acids were causally associated with the increased risk of various pancreatitis. Dietary supplementation of … See more This study gave concrete evidence showing the strong causal effects of triglycerides, particularly triglycerides in HDL particles, on the risk of pancreatitis. Moreover, we observed traits related with increased fatty acid … See more Webbisallylic methylene groups (i.e. methylene groups with two adjacent double bonds) of the hydrocarbon chains by NO2 (reaction 1). The resulting lipid radical rearranges (reaction 2) under transformation of the isolated double bond system into a conjugated one and adds molecular oxygen (reaction 3), yielding a lipid peroxy radical. This compound ... circle around a cross
A Bisallylic Mini-lipoxygenase from Cyanobacterium
WebBisallylic groups are readily oxidized because their electrons are pulled to either side by the adjacent double bonds, resulting in weakened bond energies [34]. There are 3 events involved in the free radical-mediated lipid peroxidation chain mechanism: initiation, propagation, and WebRates of peroxidation of PCs with multiple bisallylic groups (i.e. 20:4n-6 and 22:6n-3) peroxidized at 2-3 times the rate per bisallylic bond than the same phospholipid with 18:2n-6. The results ... WebFeb 1, 2015 · Rates of peroxidation of PCs with multiple bisallylic groups (i.e. 20:4n-6 and 22:6n-3) peroxidized at 2-3 times the rate per bisallylic bond than the same … circlearoundofficial