Photocaged quinone methide
WebMar 21, 2016 · Upon photoactivation, FnbY generated a reactive quinone methide (QM), which selectively reacted with nine natural amino acid residues placed in proximity in proteins directly in live cells. WebAug 22, 2024 · Liu, J. et al. Photocaged Quinone Methide Crosslinkers for Light-Controlled C hemical Crosslinking of Protein-Protein and Protein-DNA Complexes. Angew. Chem. Int. Ed. 58, 18839-18843 (2024).
Photocaged quinone methide
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WebOct 23, 2024 · A lightbulb moment: Photocaged quinone methide (PQM) crosslinkers that target nine nucleophilic amino acids, including Gln, Arg, and Asn, have been developed. … WebSep 11, 2024 · Upon photoactivation, FnbY generated a reactive quinone methide (QM), which selectively reacted with nine natural amino acid residues placed in proximity in …
WebJun 4, 2024 · Here we report the genetic encoding of (2 R)-2-amino-3-fluoro-3-(4-((2-nitrobenzyl)oxy) phenyl) propanoic acid (FnbY) in Escherichia coli and mammalian cells. … WebSep 25, 2024 · Here we report a new chemical conjugation method which photocages highly reactive but chemically selective moieties, enabling the use of protein-inert amines for …
WebOct 23, 2024 · Photocaged Quinone Methide Crosslinkers for Light‐Controlled Chemical Crosslinking of Protein–Protein and Protein–DNA Complexes Dr. Jun Liu University of … WebJan 4, 2024 · Visible-light-induced [6+4] cycloaddition reactions of ortho-quinone methides have been developed.The reaction of ortho-quinone methides with pentafulvenes in the …
WebJun 6, 2024 · Upon photoactivation, FnbY generated a reactive quinone methide (QM), which selectively reacted with nine natural amino acid residues placed in proximity in …
WebOct 1, 2024 · Here we report photocaged quinone methide (PQM)‐based cross‐linkers that are able to multitarget nine nucleophilic residues through specific Michael addition. In … jonesboro forecastWebApr 1, 2024 · Quinone methide precursors 12 ‐ 14 protected with alkyldithiomethyl groups of increasing steric demand have been synthesized and converted into PNA conjugates 3 ‐ 5 . jonesboro flower shopsWebNational Center for Biotechnology Information how to install cufflinks in anacondaWeb中南大学材料科学与工程学院. 被引频次. 471. 成果数. 75. h指数. 13. g指数. 19. how to install cufflinks in jupyter notebookWebJun 10, 2024 · Highly reactive photothermal carbon dots are promising building blocks for functional plastics but remain challenging. Here, we present carbon dots with photocaged reactivity (P-CDs) for producing robust solar-thermal plastics. Stable P-CDs released reactive aldehyde upon light irradiation, which efficiently reacted with amino groups in the plastic … how to install cudnn for tensorflowWebOct 23, 2024 · Herein, we report photocaged quinone methide (PQM)-based crosslinkers that target nine nucleophilic residues through Michael addition, including Gln, Arg, and Asn, which are inaccessible to existing chemical crosslinkers. PQM … jonesboro foot clinicWebPhotocaged Quinone Methide Crosslinkers for Light-Controlled Chemical Crosslinking of Protein-Protein and Protein-DNA Complexes. Photocaged Quinone Methide Crosslinkers … how to install cudnn windows 10