Webcd36和配体凝血酶敏感蛋白(tsp)-1共同表达在啮齿类动物和牛卵巢的颗粒细胞和卵泡膜细胞 [3,6] ,二者共同表达在卵泡发生的各个时期,cd36通过与tsp-1结合调节卵巢血管的形成,进一步调节卵泡的发育和黄体的形成,因此,cd36在调节卵巢细胞功能和卵泡生长过程中是一个重要的调节子 。 WebPlatelet glycoprotein 4 (CD36) (or fatty acyl translocase [FAT], or scavenger receptor class B, member 3 [SCARB3]) is an essential cell surface and skeletal muscle outer mitochondrial membrane glycoprotein involved in multiple functions in the body. CD36 serves as a ligand receptor of thrombospondin, long chain fatty acids, oxidized low density lipoproteins …
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WebJul 23, 2024 · tsp-1为内源性血管生成抑制因子,内皮血管为主要分泌部位,生成后能够与cd36相结合,对新生血管形成过程起一定抑制作用,同时能够诱导内皮细胞的凋亡。 WebMar 21, 2024 · Ligand for receptor CD36 (PubMed:1371676, 10613822, 11134179). Involved in inducing apoptosis in podocytes in response to elevated free fatty acids, acting via … jashinchan.com
Thrombospondin 2 Regulates Cell Proliferation Induced by Rac1 …
WebUntitled - Free download as Powerpoint Presentation (.ppt), PDF File (.pdf), Text File (.txt) or view presentation slides online. WebThrombospondin-1 (TSP1) is a glycoprotein involved in various biological processes which, by interacting with vascular factors (e.g., vWF and fibrinogen), can modulate platelet activity. Platelets not only secrete TSP1 from their α-granules upon activation but also bind TSP1 through several receptors, such as the glycoprotein Ib-V-IX complex, CD47, integrins, and … WebAlthough CD36 is generally recognized to be an inhibitory signaling receptor for thrombospondin-1 (TSP1), the molecular mechanism for transduction of this signal … jashinchan - 7th devil